Aims and Scope
Editor's Choice
Targeting Melanoma with Cancer-Killing Viruses
Tiantian Zhang, Yogesh R. Suryawanshi, Helene M. Woyczesczyk, Karim EssaniMarch 31, 2017
The Open Virology Journal is an Open Access online journal which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of virology. The journal encourages submissions related to the following fields:
The Open Virology Journal, a peer-reviewed journal, is an important and reliable source of current information on important developments in the field. The emphasis will be on publishing quality papers rapidly and making them freely available to researchers worldwide.
Melanoma is the deadliest skin cancer with ever-increasing incidence. Despite the development in diagnostics and therapies, metastatic melanoma is still associated with significant morbidity and mortality. Oncolytic viruses (OVs) represent a class of novel therapeutic agents for cancer by possessing two closely related properties for tumor reduction: virus-induced lysis of tumor cells and induction of host anti-tumor immune responses. A variety of viruses, either in “natural” or in genetically modified forms, have exhibited a remarkable therapeutic efficacy in regressing melanoma in experimental and/or clinical studies. This review provides a comprehensive summary of the molecular and cellular mechanisms of action of these viruses, which involve manipulating and targeting the abnormalities of melanoma, and can be categorized as enhancing viral tropism, targeting the tumor microenvironment and increasing the innate and adaptive antitumor responses. Additionally, this review describes the “biomarkers” and deregulated pathways of melanoma that are responsible for melanoma initiation, progression and metastasis. Advances in understanding these abnormalities of melanoma have resulted in effective targeted and immuno-therapies, and could potentially be applied for engineering OVs with enhanced oncolytic activity in future.
 | The Open Virology JournalISSN: 1874-3579Volume: 15, 2021 |
 | L. Andreoletti Department of Virology University Champagne-Ardenne France | |
View Biography × Biography of L. Andreoletti
Department of Virology, University Champagne-Ardenne, , France | ||
Bentham Open is pleased to welcome Sultan Idris University of Education (UPSI), Malaysia as Institutional Member. The partnership allows the researchers from the university to publish their research under an Open Access license with specified fee discounts. Bentham Open welcomes institutions and organizations from world over to join as Institutional Member and avail a host of benefits for their researchers.
Sultan Idris University of Education (UPSI) was established in 1922 and was known as the first Teacher Training College of Malaya. It is known as one of the oldest universities in Malaysia. UPSI was later upgraded to a full university institution on 1 May, 1997, an upgrade from their previous college status. Their aim to provide exceptional leadership in the field of education continues until today and has produced quality graduates to act as future educators to students in the primary and secondary level.
Bentham Open publishes a number of peer-reviewed, open access journals. These free-to-view online journals cover all major disciplines of science, medicine, technology and social sciences. Bentham Open provides researchers a platform to rapidly publish their research in a good-quality peer-reviewed journal. All peer-reviewed accepted submissions meeting high research and ethical standards are published with free access to all.
Bentham Open is pleased to announce an Institutional Member partnership with the Ministry of Health, Jordan. The partnership provides the opportunity to the researchers, from the university, to publish their research under an Open Access license with specified fee concessions. Bentham Open welcomes institutions and organizations from the world over to join as Institutional Member and avail a host of benefits for their researchers.
The first Ministry of Health in Jordan was established in 1950. The Ministry began its duties in 1951, the beginning of the health development boom in Jordan. The first accomplishment was the establishment of six departments in the districts headed by a physician and under the central administration of the Ministry. The Ministry of Health undertakes all health affairs in the Kingdom and its accredited hospitals include AL-Basheer Hospital, Zarqa Governmental Hospital, University of Jordan Hospital, Prince Hashem Military Hospital and Karak Governmental Hospital.
Bentham Open publishes a number of peer-reviewed, open access journals. These free-to-view online journals cover all major disciplines of science, medicine, technology and social sciences. Bentham Open provides researchers a platform to rapidly publish their research in a good-quality peer-reviewed journal. All peer-reviewed, accepted submissions meeting high research and ethical standards are published with free access to all.
Bentham Open is pleased to announce an Institutional Member partnership with the Porto University, Faculty of Dental Medicine (FMDUP). The partnership provides the opportunity to the researchers, from the university, to publish their research under an Open Access license with specified fee concessions. Bentham Open welcomes institutions and organizations from world over to join as Institutional Member and avail a host of benefits for their researchers.
The Porto University was founded in 1911. Porto University create scientific, cultural and artistic knowledge, higher education training strongly anchored in research, the social and economic valorization of knowledge and active participation in the progress of the communities in which it operates.
Bentham Open publishes a number of peer-reviewed, open access journals. These free-to-view online journals cover all major disciplines of science, medicine, technology and social sciences. Bentham Open provides researchers a platform to rapidly publish their research in a good-quality peer-reviewed journal. All peer-reviewed accepted submissions meeting high research and ethical standards are published with free access to all.
The Open Virology Journal is an Open Access online journal, which publishes research articles, reviews, letters, case reports and guest-edited single topic issues in all areas of virology. Bentham Open ensures speedy peer review process and accepted papers are published within 2 weeks of final acceptance.
The Open Virology Journal is committed to ensuring high quality of research published. We believe that a dedicated and committed team of editors and reviewers make it possible to ensure the quality of the research papers. The overall standing of a journal is in a way, reflective of the quality of its Editor(s) and Editorial Board and its members.
The Open Virology Journal is seeking energetic and qualified researchers to join its editorial board team as Editorial Board Members or reviewers.
The essential criteria to become Editorial Board Members of The Open Virology Journal are as follows:
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If you are interested in becoming our Editorial Board member, please submit the following information to info@benthamopen.net. We will respond to your inquiry shortly.
Email subject: Editorial Board Member Application
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