High Prevalence of Hepatitis B Virus Infection in the Age Range of 20-39 Years Old Individuals in Lome



Malewe Kolou1, 2, *, Gnatoulma Katawa3, Mounerou Salou2, Komlan Selom Gozo-Akakpo3, Sika Dossim2, Alexander Kwarteng4, Mireille Prince-David2
1 Centre Hospitalier Universitaire (CHU) Campus, Lome, Togo
2 Faculte des Sciences de la Santé (FSS), Universite de Lome, Togo
3 Ecole Superieure des Techniques Biologiques et Alimentaires (ESTBA), Universite de Lome, Togo
4 Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital of Bonn, Germany


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© Kolou et al.; Licensee Bentham Open

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the CHU Campus Faculte des Sciences de la Santé, Universite de Lome; Agoe Logope 13 BP 378 Lome, Togo; Tel: +228 90106600; E-mails: koloumalewe@hotmail.fr, koloumalewe@gmail.com


Abstract

Background:

Hepatitis B is a liver infection caused by the hepatitis B virus (HBV). It affects all women and men irrespective of age. Although sub-Saharan Africa is an area of high prevalence of this disease, data on the prevalence of acute and chronic HBV infections in this region remain to be widely documented.

Objective:

This study aimed to investigate the prevalence of HBV in relation to age in Centre Hospitalier Universitaire Campus (CHU-C), one of the two teaching hospitals of Lome, Togo.

Method:

The present study is a cross-sectional study about the prevalence of hepatitis B surface antigen (HBsAg) carriage from 2009 to 2011. All study participants were screened for HBsAg at the Immunology laboratory of CHU Campus of Lome.

Results:

One thousand two hundred individuals were screened for HBsAg from 2009-2011. The overall prevalence of HBV infection was 19.08%. This prevalence was significantly higher in men (25.00%) than women (14.80%). The highest prevalence of HBV was observed in age range of 20-29 years and 30-39 years with respectively 26.33% and 21.67%. The lowest prevalence was 6.08%, found in people over 50 years. Concerning the clinical indication of the test, the prevalence during the clinical abnormalities related to liver (CARL) was the highest (26.21%), followed by the systematic screening (SS) with 20.25% while the pre-operative assessment (POA) showed the lowest prevalence with 5.56%.

Conclusion:

The study shows the high prevalence of HBsAg carriage in young people. This could be used to enhance prevention and treatment of HBV infection in Togo.

Keywords: Age range, HBs antigen, Hepatitis B virus, Prevalence, Togo.